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Relevance of FXR-p62/SQSTM1 pathway for survival and protection of mouse hepatocytes and liver, especially with steatosis

BACKGROUND: Liver injury and regeneration involve complicated processes and are affected by various physio-pathological conditions. Surgically, severe liver injury after surgical resection often leads to fatal liver failure, especially with some underlying pathological conditions such as steatosis....

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Pubblicato in:BMC Gastroenterol
Autori principali: Haga, Sanae, Yimin, Ozaki, Michitaka
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237313/
https://ncbi.nlm.nih.gov/pubmed/28086800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12876-016-0568-3
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