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Is treatment-resistant schizophrenia categorically distinct from treatment-responsive schizophrenia? a systematic review

BACKGROUND: Schizophrenia is a highly heterogeneous disorder, and around a third of patients are treatment-resistant. The only evidence-based treatment for these patients is clozapine, an atypical antipsychotic with relatively weak dopamine antagonism. It is plausible that varying degrees of respons...

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Bibliographic Details
Published in:BMC Psychiatry
Main Authors: Gillespie, Amy L., Samanaite, Ruta, Mill, Jonathan, Egerton, Alice, MacCabe, James H.
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237235/
https://ncbi.nlm.nih.gov/pubmed/28086761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12888-016-1177-y
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