Cloning and functional characterization of LCR-F1: a bZIP transcription factor that activates erythroid-specific, human globin gene expression.

DNase I hypersensitive site 2 (HS 2) of the human beta-globin Locus Control Region (LCR) directs high level expression of the beta-globin gene located 50 kilobases downstream. Experiments in cultured cells and in transgenic mice demonstrate that duplicated AP1-like sites in HS 2 are required for thi...

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Bibliographic Details
Main Authors: Caterina, J J, Donze, D, Sun, C W, Ciavatta, D J, Townes, T M
Format: Artigo
Language:Inglês
Published: 1994
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC523699/
https://ncbi.nlm.nih.gov/pubmed/8036168
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