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The acute inhibition of enteric glial metabolism with fluoroacetate alters calcium signaling, hemichannel function, and the expression of key proteins

Glia play key roles in the regulation of neurotransmission in the nervous system. Fluoroacetate (FA) is a metabolic poison widely used to study glial functions by disrupting the tricarboxylic acid cycle enzyme aconitase. Despite the widespread use of FA, the effects of FA on essential glial function...

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Bibliografiske detaljer
Udgivet i:J Neurophysiol
Main Authors: McClain, Jonathon L., Gulbransen, Brian D.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5236112/
https://ncbi.nlm.nih.gov/pubmed/27784805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00507.2016
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