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The Importance of l-Arginine:NO:cGMP Pathway in Tolerance to Flunitrazepam in Mice

The goal of the study was to investigate the effects of drugs modifying l-arginine:NO:cGMP pathway on the development of tolerance to flunitrazepam (FNZ)-induced motor impairment in mice. FNZ-induced motor incoordination was assessed on the 1st and 8th days of experiment, using the rotarod and chimn...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neurotox Res
Hauptverfasser: Talarek, Sylwia, Listos, Joanna, Orzelska-Gorka, Jolanta, Jakobczuk, Malgorzata, Kotlinska, Jolanta, Biala, Grazyna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5236083/
https://ncbi.nlm.nih.gov/pubmed/27957675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-016-9688-3
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