Enhanced GABAergic inhibition preserves hippocampal structure and function in a model of epilepsy.

Extensive electrical stimulation of the perforant pathway input to the hippocampus results in a characteristic pattern of neuronal death, which is accompanied by an impairment of cognitive functions similar to that seen in human temporal lobe epilepsy. The excitotoxic hypothesis of epileptic cell de...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ylinen, A M, Miettinen, R, Pitkänen, A, Gulyas, A I, Freund, T F, Riekkinen, P J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52359/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1652757/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.17.7650
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