Targeted Inhibition of Pancreatic Acinar Cell Calcineurin Is a Novel Strategy to Prevent Post-ERCP Pancreatitis

BACKGROUND & AIMS: There is a pressing need to develop effective preventative therapies for post–endoscopic retrograde cholangiopancreatography pancreatitis (PEP). We showed that early PEP events are induced through the calcium-activated phosphatase calcineurin and that global calcineurin deleti...

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Gepubliceerd in:Cell Mol Gastroenterol Hepatol
Hoofdauteurs: Orabi, Abrahim I., Wen, Li, Javed, Tanveer A., Le, Tianming, Guo, Ping, Sanker, Subramaniam, Ricks, David, Boggs, Kristy, Eisses, John F., Castro, Carlos, Xiao, Xiangwei, Prasadan, Krishna, Esni, Farzad, Gittes, George K., Husain, Sohail Z.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2016
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5235344/
https://ncbi.nlm.nih.gov/pubmed/28090570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2016.08.006
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