Ectopic fat deposition contributes to age-associated pathology in Caenorhabditis elegans

Age-dependent collapse of lipid homeostasis results in spillover of lipids and excessive fat deposition in nonadipose tissues. Ectopic fat contributes to lipotoxicity and has been implicated in the development of a metabolic syndrome that increases risk of age-associated diseases. However, the molec...

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Bibliographic Details
Published in:J Lipid Res
Main Authors: Palikaras, Konstantinos, Mari, Meropi, Petanidou, Barbara, Pasparaki, Angela, Filippidis, George, Tavernarakis, Nektarios
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2017
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234711/
https://ncbi.nlm.nih.gov/pubmed/27884963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M069385
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