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(−)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling
RATIONALE: (−)-Stepholidine is a tetrahydroberberine alkaloid that is known to interact with dopamine receptors and has also been proposed as a novel antipsychotic agent. Its suggested novelty lies in the fact that it has been proposed to have D1-like receptor agonist and D2-like receptor antagonist...
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| Publicado no: | Psychopharmacology (Berl) |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5234683/ https://ncbi.nlm.nih.gov/pubmed/25231919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3726-8 |
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