טוען...

(−)-Stepholidine is a potent pan-dopamine receptor antagonist of both G protein- and β-arrestin-mediated signaling

RATIONALE: (−)-Stepholidine is a tetrahydroberberine alkaloid that is known to interact with dopamine receptors and has also been proposed as a novel antipsychotic agent. Its suggested novelty lies in the fact that it has been proposed to have D1-like receptor agonist and D2-like receptor antagonist...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Psychopharmacology (Berl)
Main Authors: Meade, Julie A., Free, R. Benjamin, Miller, Nicole R., Chun, Lani S., Doyle, Trevor B., Moritz, Amy E., Conroy, Jennie L., Watts, Val J., Sibley, David R.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234683/
https://ncbi.nlm.nih.gov/pubmed/25231919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3726-8
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