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Exploring the potential of variola virus infection of cynomolgus macaques as a model for human smallpox

Smallpox virus (variola) poses a significant threat as an agent of bioterrorism. To mitigate this risk, antiviral drugs and an improved vaccine are urgently needed. Satisfactory demonstration of protective efficacy against authentic variola will require development of an animal model in which variol...

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Detalles Bibliográficos
Main Authors: Jahrling, Peter B., Hensley, Lisa E., Martinez, Mark J., LeDuc, James W., Rubins, Kathleen H., Relman, David A., Huggins, John W.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC523454/
https://ncbi.nlm.nih.gov/pubmed/15477589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405954101
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