Calprotectin (S100A8/A9) has the strongest association with ultrasound-detected synovitis and predicts response to biologic treatment: results from a longitudinal study of patients with established rheumatoid arthritis

BACKGROUND: Calprotectin (S100A8/A9 or MRP8/14) and S100A12 (leukocyte-derived proteins), interleukin 6 (IL-6) and vascular endothelial growth factor (VEGF) are markers of inflammation and angiogenesis. Ultrasound (US) is sensitive for detection of greyscale synovitis and power Doppler (PD) vascular...

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Détails bibliographiques
Publié dans:Arthritis Res Ther
Auteurs principaux: Nordal, Hilde Haugedal, Brokstad, Karl Albert, Solheim, Magne, Halse, Anne-Kristine, Kvien, Tore K., Hammer, Hilde Berner
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5234113/
https://ncbi.nlm.nih.gov/pubmed/28081709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1201-0
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