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Single PA mutation as a high yield determinant of avian influenza vaccines

Human infection with an avian influenza virus persists. To prepare for a potential outbreak of avian influenza, we constructed a candidate vaccine virus (CVV) containing hemagglutinin (HA) and neuraminidase (NA) genes of a H5N1 virus and evaluated its antigenic stability after serial passaging in em...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Lee, Ilseob, Il Kim, Jin, Park, Sehee, Bae, Joon-Yong, Yoo, Kirim, Yun, Soo-Hyeon, Lee, Joo-Yeon, Kim, Kisoon, Kang, Chun, Park, Man-Seong
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233958/
https://ncbi.nlm.nih.gov/pubmed/28084423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40675
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