Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein.

Senile plaques are polymorphous beta-amyloid protein deposits found in the brain in Alzheimer disease and normal aging. This beta-amyloid protein is derived from a larger precursor molecule of which neurons are the principal producers in brain. We found that amyloid precursor protein (APP)-immunorea...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Cras, P, Kawai, M, Lowery, D, Gonzalez-DeWhitt, P, Greenberg, B, Perry, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52339/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1652752/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.17.7552
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