Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines

Advax, a delta inulin-derived microparticle, has been developed as an adjuvant for several vaccines. However, its immunological characteristics and potential mechanism of action are yet to be elucidated. Here, we show that Advax behaves as a type-2 adjuvant when combined with influenza split vaccine...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Hayashi, Masayuki, Aoshi, Taiki, Haseda, Yasunari, Kobiyama, Kouji, Wijaya, Edward, Nakatsu, Noriyuki, Igarashi, Yoshinobu, Standley, Daron M., Yamada, Hiroshi, Honda-Okubo, Yoshikazu, Hara, Hiromitsu, Saito, Takashi, Takai, Toshiyuki, Coban, Cevayir, Petrovsky, Nikolai, Ishii, Ken J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233800/
https://ncbi.nlm.nih.gov/pubmed/27919753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.11.015
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