Prolonged fibroblast growth factor 19 response in patients with primary sclerosing cholangitis after an oral chenodeoxycholic acid challenge

BACKGROUND: Bile salts likely contribute to liver injury in patients with primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC). Fibroblast growth factor 19 (FGF19) is a bile salt-induced enterokine with hepatoprotective potential as it suppresses de novo bile salt synthesis. He...

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Detalhes bibliográficos
Publicado no:Hepatol Int
Principais autores: Zweers, Serge J., de Vries, Elisabeth M., Lenicek, Martin, Tolenaars, Dagmar, de Waart, D. Rudi, Koelfat, Kiran V. K., Groen, Albert K., Olde Damink, Steven W. M., Beuers, Ulrich, Ponsioen, Cyriel, Jansen, Peter L. M., Schaap, Frank G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer India 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233735/
https://ncbi.nlm.nih.gov/pubmed/27696157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12072-016-9769-7
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