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P53 mutations and cancer: a tight linkage
P53 is often mutated in solid tumors, in fact, somatic changes involving the gene encoding for p53 (TP53) have been discovered in more than 50% of human malignancies and several data confirmed that p53 mutations represent an early event in cancerogenesis. Main p53 functions consist in cell cycle arr...
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| 出版年: | Ann Transl Med |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
AME Publishing Company
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5233470/ https://ncbi.nlm.nih.gov/pubmed/28149884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2016.12.40 |
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