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Reduced Socs3 expression in adipose tissue protects female mice against obesity-induced insulin resistance

AIMS/HYPOTHESIS: Inflammation in obesity increases the levels of the suppressor of cytokine signalling-3 (SOCS3) protein in adipose tissue, but the physiological importance of this protein in regulating whole-body insulin sensitivity in obesity is not known. METHODS: We generated Socs3 floxed (wild-...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Palanivel, R., Fullerton, M. D., Galic, S., Honeyman, J., Hewitt, K. A., Jorgensen, S. B., Steinberg, G. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233443/
https://ncbi.nlm.nih.gov/pubmed/22872213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2665-3
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