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Functional significance of an overlapping consensus binding motif for Sp1 and Zif268 in the murine adenosine deaminase gene promoter.

The murine adenosine deaminase (ADA) gene has a (G + C)-rich promoter that can support diverse tissue-specific gene expression. By using deletion and mutation analyses, we have identified a cis-acting "repressor" element located immediately upstream of the proximal Sp1 binding site in the ADA gene p...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Ackerman, S L, Minden, A G, Williams, G T, Bobonis, C, Yeung, C Y
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52333/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1881892/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.17.7523
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