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Statin Compounds Reduce Human Immunodeficiency Virus Type 1 Replication by Preventing the Interaction between Virion-Associated Host Intercellular Adhesion Molecule 1 and Its Natural Cell Surface Ligand LFA-1

A variety of host factors, including membrane proteins acquired by human immunodeficiency virus type 1 (HIV-1), play a dominant role in HIV-1 adsorption onto host cells. Examples include the integrin intercellular adhesion molecule 1 (ICAM-1), which, once acquired by HIV-1, promotes virus infectivit...

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Detalhes bibliográficos
Main Authors: Giguère, Jean-François, Tremblay, Michel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC523291/
https://ncbi.nlm.nih.gov/pubmed/15479847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.21.12062-12065.2004
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