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One-Way Allosteric Communication between the Two Disulfide Bonds in Tissue Factor
Tissue factor (TF) is a transmembrane glycoprotein that plays distinct roles in the initiation of extrinsic coagulation cascade and thrombosis. TF contains two disulfide bonds, one each in the N-terminal and C-terminal extracellular domains. The C-domain disulfide, Cys186-Cys209, has a −RHStaple con...
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| Опубликовано в: : | Biophys J |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Biophysical Society
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5232894/ https://ncbi.nlm.nih.gov/pubmed/28076818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.12.003 |
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