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Selection for Loss of Ref1 Activity in Human Cells Releases Human Immunodeficiency Virus Type 1 from Cyclophilin A Dependence during Infection

Capsid (CA)-specific restrictions are determinants of retroviral tropism in mammalian cells. One such restriction, human Ref1, targets strains of murine leukemia virus bearing an arginine at CA residue 110 (N-MLV), resulting in decreased accumulation of viral cDNA. The cellular factors accounting fo...

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Detalhes bibliográficos
Principais autores: Sayah, David M., Luban, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC523284/
https://ncbi.nlm.nih.gov/pubmed/15479848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.21.12066-12070.2004
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