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Identification of a Negative Regulatory Element in the Epstein-Barr Virus Zta Transactivation Domain That Is Regulated by the Cell Cycle Control Factors c-Myc and E2F1

Reactivation in Epstein-Barr virus (EBV) is closely associated with a G(0)/G(1) cell cycle arrest which can be induced either by lytic cycle-inducing agents or by the immediate-early gene product Zta. Accumulating evidence shows that in epithelial cells, downregulation of the proto-oncogene, c-myc,...

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Detalhes bibliográficos
Main Authors: Lin, Zhen, Yin, Qinyan, Flemington, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC523277/
https://ncbi.nlm.nih.gov/pubmed/15479836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.21.11962-11971.2004
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