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Evidence for both Lytic Replication and Tightly Regulated Human Herpesvirus 8 Latency in Circulating Mononuclear Cells, with Virus Loads Frequently below Common Thresholds of Detection

To address whether human herpesvirus 8 (HHV-8) DNA in peripheral blood mononuclear cells (PBMCs) might be the product of latent or lytic infection and to shed light on sporadic detection of HHV-8 DNA in individuals seropositive for the virus, we studied the frequency of infected cells, total virus l...

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Detalhes bibliográficos
Main Authors: Martró, Elisa, Cannon, Michael J., Dollard, Sheila C., Spira, Thomas J., Laney, A. Scott, Ou, Chin-Yih, Pellett, Philip E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC523251/
https://ncbi.nlm.nih.gov/pubmed/15479812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.21.11707-11714.2004
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