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Increased Stability of bmr3 mRNA Results in a Multidrug-Resistant Phenotype in Bacillus subtilis

A spontaneous mutant isolated in the presence of a high concentration of puromycin acquired a multidrug-resistant phenotype. Expression of the bmr3 gene was dramatically increased. A base substitution, T to A at the +4 position, detected in the mutant resulted in the stabilization of bmr3 mRNA.

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Hlavní autoři: Ohki, Reiko, Tateno, Kozue
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC523217/
https://ncbi.nlm.nih.gov/pubmed/15489457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.21.7450-7455.2004
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