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Membrane Topology Analysis of Cyclic Glucan Synthase, a Virulence Determinant of Brucella abortus

Brucella abortus cyclic glucan synthase (Cgs) is a 316-kDa (2,831-amino-acid) integral inner membrane protein that is responsible for the synthesis of cyclic β-1,2-glucan by a novel mechanism in which the enzyme itself acts as a protein intermediate. B. abortus Cgs uses UDP-glucose as a sugar donor...

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Detalhes bibliográficos
Main Authors: Ciocchini, Andrés E., Roset, Mara S., Iñón de Iannino, Nora, Ugalde, Rodolfo A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC523211/
https://ncbi.nlm.nih.gov/pubmed/15489431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.21.7205-7213.2004
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