Dermal γδ T Cells Do Not Freely Re-Circulate Out of Skin and Produce IL-17 to Promote Neutrophil Infiltration during Primary Contact Hypersensitivity

The role of mouse dermal γδ T cells in inflammatory skin disorders and host defense has been studied extensively. It is known that dendritic epidermal T cells (DETC) have a monomorphic γδ T cell receptor (TCR) and reside in murine epidermis from birth. We asked if dermal γδ cells freely re-circulate...

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Vydáno v:PLoS One
Hlavní autoři: Jiang, Xiaodong, Park, Chang Ook, Geddes Sweeney, Jenna, Yoo, Min Jae, Gaide, Olivier, Kupper, Thomas Seth
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5230790/
https://ncbi.nlm.nih.gov/pubmed/28081153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169397
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