Effect of Dosage on Immunogenicity of a Vi Conjugate Vaccine Injected Twice into 2- to 5-Year-Old Vietnamese Children

In a double-blind, randomized, and placebo-controlled previous trial, the efficacy of Vi-rEPA for typhoid fever in 2- to 5-year-olds was 89.0% for 46 months. Vi-rEPA contained 25 μg of Vi and induced a greater-than-eightfold rise in immunoglobulin G (IgG) anti-Vi in all of the vaccinees tested. In t...

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Bibliographische Detailangaben
Hauptverfasser: Canh, Do Gia, Lin, Feng-ying (Kimi), Thiem, Vu Dinh, Trach, Dang Duc, Trong, Nguyen Dinh, Mao, Nguyen Duc, Hunt, Steven, Schneerson, Rachel, Robbins, John B., Chu, Chiayung, Shiloach, Joseph, Bryla, Dolores A., Bonnet, Marie-Claude, Schulz, Dominique, Szu, Shousun C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC523060/
https://ncbi.nlm.nih.gov/pubmed/15501790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.11.6586-6588.2004
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