Effects of vlsE Complementation on the Infectivity of Borrelia burgdorferi Lacking the Linear Plasmid lp28-1

The loss of linear plasmid lp28-1, which contains the vls antigenic variation locus, is associated with reduced infectivity of Borrelia burgdorferi in immunocompetent mice. The recombinant shuttle vector pBBE22, which includes the virulence determinant BBE22 from lp25 and restores infectivity to rea...

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Main Authors: Lawrenz, Matthew B., Wooten, R. Mark, Norris, Steven J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC523020/
https://ncbi.nlm.nih.gov/pubmed/15501789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.11.6577-6585.2004
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