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RNA Encoding the MPT83 Antigen Induces Protective Immune Responses against Mycobacterium tuberculosis Infection

We have previously demonstrated that vaccination of mice with plasmid DNA vectors expressing immunodominant mycobacterial genes induced cellular immune responses and significant protection against challenge with Mycobacterium tuberculosis. We demonstrate here, using in vitro-synthesized RNA, that va...

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Detalhes bibliográficos
Main Authors: Xue, Tian, Stavropoulos, Evangelos, Yang, Min, Ragno, Silvia, Vordermeier, Martin, Chambers, Mark, Hewinson, Glyn, Lowrie, Douglas B., Colston, M. Joseph, Tascon, Ricardo E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC523008/
https://ncbi.nlm.nih.gov/pubmed/15501761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.11.6324-6329.2004
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