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Human immunodeficiency virus type 1 regulator of virion expression, rev, forms nucleoprotein filaments after binding to a purine-rich "bubble" located within the rev-responsive region of viral mRNAs.

The human immunodeficiency virus type 1 rev protein binds with high affinity (Kd less than 1-3 nM) to a purine-rich "bubble" containing bulged GG and GUA residues on either side of a double-helical RNA stem-loop located toward the 5' end of rev-response element RNA. High-affinity rev binding is main...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Heaphy, S, Finch, J T, Gait, M J, Karn, J, Singh, M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1991
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52296/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1871141/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.16.7366
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