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Untangling Basal Ganglia Network Dynamics and Function: Role of Dopamine Depletion and Inhibition Investigated in a Spiking Network Model

The basal ganglia are a crucial brain system for behavioral selection, and their function is disturbed in Parkinson’s disease (PD), where neurons exhibit inappropriate synchronization and oscillations. We present a spiking neural model of basal ganglia including plausible details on synaptic dynamic...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Lindahl, Mikael, Hellgren Kotaleski, Jeanette
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5228592/
https://ncbi.nlm.nih.gov/pubmed/28101525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0156-16.2016
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