Time-dependent transition of the immunoglobulin G subclass and immunoglobulin E response in cancer patients vaccinated with cholesteryl pullulan-melanoma antigen gene-A4 nanogel

A phase I+II clinical trial of vaccination with MAGE-A4 protein complexed with cholesteryl pullulan melanoma antigen gene-A4 nanogel (CHP-MAGE-A4) is currently underway in patients with MAGE-A4-expressing cancer. In the present study, the primary phase I endpoint was to test the safety of the admini...

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Veröffentlicht in:Oncol Lett
Hauptverfasser: Kyogoku, Noriaki, Ikeda, Hiroaki, Tsuchikawa, Takahiro, Abiko, Takehiro, Fujiwara, Aki, Maki, Takehiro, Yamamura, Yoshiyuki, Ichinokawa, Masaomi, Tanaka, Kimitaka, Imai, Naoko, Miyahara, Yoshihiro, Kageyama, Shinichi, Shiku, Hiroshi, Hirano, Satoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2016
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5228337/
https://ncbi.nlm.nih.gov/pubmed/28105158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5253
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