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Anticancer effects of valproic acid on oral squamous cell carcinoma via SUMOylation in vivo and in vitro

Aberrant histone deacetylase (HDAC) has a key role in the neoplastic process associated with the epigenetic patterns of tumor-related genes. The present study was performed to investigate the effects and determine the mechanism of action of the HDAC inhibitor, valproic acid (VPA), on the CAL27 cell...

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Dades bibliogràfiques
Publicat a:Exp Ther Med
Autors principals: Sang, Zhijian, Sun, Yang, Ruan, Hong, Cheng, Yong, Ding, Xiaojun, Yu, Youcheng
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5228083/
https://ncbi.nlm.nih.gov/pubmed/28101176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3907
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