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Comparing GWAS Results of Complex Traits Using Full Genetic Model and Additive Models for Revealing Genetic Architecture

Most of the genome-wide association studies (GWASs) for human complex diseases have ignored dominance, epistasis and ethnic interactions. We conducted comparative GWASs for total cholesterol using full model and additive models, which illustrate the impacts of the ignoring genetic variants on analys...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Monir, Md. Mamun, Zhu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5227710/
https://ncbi.nlm.nih.gov/pubmed/28079101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38600
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