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In Silico Analysis of SNPs in PARK2 and PINK1 Genes That Potentially Cause Autosomal Recessive Parkinson Disease

Introduction. Parkinson's disease (PD) is a common neurodegenerative disorder. Mutations in PINK1 are the second most common agents causing autosomal recessive, early onset PD. We aimed to identify the pathogenic SNPs in PARK2 and PINK1 using in silico prediction software and their effect on th...

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Библиографические подробности
Опубликовано в: :Adv Bioinformatics
Главные авторы: Bakhit, Yousuf Hasan Yousuf, Ibrahim, Mohamed Osama Mirghani, Amin, Mutaz, Mirghani, Yousra Abdelazim, Hassan, Mohamed Ahmed Salih
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5227114/
https://ncbi.nlm.nih.gov/pubmed/28127307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9313746
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