Cellular aging contributes to failure of cold-induced beige adipocyte formation in old mice and humans

Cold temperatures induce progenitor cells within white adipose tissue to form beige adipocytes that burn energy and generate heat, a potential anti-diabesity therapy. However, the potential to form cold-induced beige adipocytes declines with age. This creates a clinical roadblock to potential therap...

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Udgivet i:Cell Metab
Main Authors: Berry, Daniel C., Jiang, Yuwei, Arpke, Robert W., Close, Elizabeth L., Uchida, Aki, Reading, David, Berglund, Eric D., Kyba, Michael, Graff, Jonathan M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226893/
https://ncbi.nlm.nih.gov/pubmed/27889388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.10.023
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