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Trial of Amitriptyline, Topiramate, and Placebo for Pediatric Migraine

BACKGROUND: Which, medication, if any, to use to prevent the headache of pediatric migraine has not been established. METHODS: We conducted a randomized, double-blind, placebo-controlled trial of amitriptyline (1 mg per kilogram of body weight per day), topiramate (2 mg per kilogram per day), and pl...

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Detalles Bibliográficos
Publicado en:N Engl J Med
Autores principales: Powers, Scott W., Coffey, Christopher S., Chamberlin, Leigh A., Ecklund, Dixie J., Klingner, Elizabeth A., Yankey, Jon W., Korbee, Leslie L., Porter, Linda L., Hershey, Andrew D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226887/
https://ncbi.nlm.nih.gov/pubmed/27788026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1610384
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