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The CCR2 Inhibitor Propagermanium Attenuates Diet-Induced Insulin Resistance, Adipose Tissue Inflammation and Non-Alcoholic Steatohepatitis

BACKGROUND AND AIM: Obese patients with chronic inflammation in white adipose tissue (WAT) have an increased risk of developing non-alcoholic steatohepatitis (NASH). The C-C chemokine receptor-2 (CCR2) has a crucial role in the recruitment of immune cells to WAT and liver, thereby promoting the infl...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mulder, Petra, van den Hoek, Anita M., Kleemann, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226841/
https://ncbi.nlm.nih.gov/pubmed/28076416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169740
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