Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells

PC12 cells are a well-established model to study how differences in signal transduction duration can elicit distinct cell behaviors. Epidermal growth factor (EGF) activates transient ERK signaling in PC12 cells that lasts 30–60 min, which in turn promotes proliferation; nerve growth factor (NGF) act...

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Veröffentlicht in:PLoS One
Hauptverfasser: Adams, Kenneth W., Kletsov, Sergey, Lamm, Ryan J., Elman, Jessica S., Mullenbrock, Steven, Cooper, Geoffrey M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226839/
https://ncbi.nlm.nih.gov/pubmed/28076410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170076
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