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Emerging Bordetella pertussis Strains Induce Enhanced Signaling of Human Pattern Recognition Receptors TLR2, NOD2 and Secretion of IL-10 by Dendritic Cells

Vaccines against pertussis have been available for more than 60 years. Nonetheless, this highly contagious disease is reemerging even in countries with high vaccination coverage. Genetic changes of Bordetella pertussis over time have been suggested to contribute to the resurgence of pertussis, as th...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Hovingh, Elise S., van Gent, Marjolein, Hamstra, Hendrik-Jan, Demkes, Marc, Mooi, Frits R., Pinelli, Elena
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226795/
https://ncbi.nlm.nih.gov/pubmed/28076445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170027
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