Combined Inhibition of the Renin-Angiotensin System and Neprilysin Positively Influences Complex Mitochondrial Adaptations in Progressive Experimental Heart Failure

BACKGROUND: Inhibitors of the renin angiotensin system and neprilysin (RAS-/NEP-inhibitors) proved to be extraordinarily beneficial in systolic heart failure. Furthermore, compelling evidence exists that impaired mitochondrial pathways are causatively involved in progressive left ventricular (LV) dy...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Grois, Laura, Hupf, Julian, Reinders, Jörg, Schröder, Josef, Dietl, Alexander, Schmid, Peter M., Jungbauer, Carsten, Resch, Markus, Maier, Lars S., Luchner, Andreas, Birner, Christoph
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226780/
https://ncbi.nlm.nih.gov/pubmed/28076404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169743
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