Both alpha-helices along the major histocompatibility complex binding cleft are required for staphylococcal enterotoxin A function.
The superantigen staphylococcal enterotoxin A (SEA) requires interaction with class II major histocompatibility complex (MHC) molecules to activate T cells. We have previously used the synthetic peptide approach to establish one side of the hypothetical class II foreign-antigen binding cleft, alpha-...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52267/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1871129/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.16.7228 |
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