Antibody neutralization of cell-surface gC1qR/HABP1/SF2-p32 prevents lamellipodia formation and tumorigenesis

We previously demonstrated that cell-surface gC1qR is a key regulator of lamellipodia formation and cancer metastasis. Here, we screened a monoclonal mouse antibody against gC1qR to prevent cell migration by neutralizing cell-surface gC1qR. The anti-gC1qR antibody prevented growth factor-stimulated...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kim, Beom-Chan, Hwang, Hyun-Jung, An, Hyoung-Tae, Lee, Hyun, Park, Jun-Sub, Hong, Jin, Ko, Jesang, Kim, Chungho, Lee, Jae-Seon, Ko, Young-Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226562/
https://ncbi.nlm.nih.gov/pubmed/27363031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10267
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