FLT3 is implicated in cytarabine transport by human equilibrative nucleoside transporter 1 in pediatric acute leukemia

FLT3 abnormalities are negative prognostic markers in acute leukemia. Infant leukemias are a subgroup with frequent MLL (KMT2A) rearrangements, FLT3 overexpression and high sensitivity to cytarabine, but dismal prognosis. Cytarabine is transported into cells by Human Equilibrative Nucleoside Transpo...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Català, Albert, Pastor-Anglada, Marçal, Caviedes-Cárdenas, Liska, Malatesta, Roberta, Rives, Susana, Vega-García, Nerea, Camós, Mireia, Fernández-Calotti, Paula
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226548/
https://ncbi.nlm.nih.gov/pubmed/27391351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10448
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