Apolipoprotein E ε4 genotype as a risk factor for cognitive decline and dementia: data from the Canadian Study of Health and Aging

BACKGROUND: Apolipoprotein E (ApoE) ε4 genotype is a well-established risk factor for Alzheimer's disease (AD). However, its effect on predicting conversion from normal to “cognitive impairment, no dementia” (CIND) and from CIND to AD is less clear. METHODS: We used a nested case–control design...

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Bibliografiska uppgifter
Huvudupphovsmän: Hsiung, Ging-Yuek R., Sadovnick, A. Dessa, Feldman, Howard
Materialtyp: Artigo
Språk:Inglês
Publicerad: Canadian Medical Association 2004
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC522651/
https://ncbi.nlm.nih.gov/pubmed/15477624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cmaj.1031789
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