Saikosaponin a inhibits LPS-induced inflammatory response by inducing liver X receptor alpha activation in primary mouse macrophages

The aim of this study was to investigate the effects of SSa on LPS-induced endotoxemia in mice and clarify the possible mechanism. An LPS-induced endotoxemia mouse model was used to confirm the anti-inflammatory activity of SSa in vivo. The primary mouse macrophages were used to investigate the mole...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wei, Zhengkai, Wang, Jingjing, Shi, Mingyu, Liu, Weijian, Yang, Zhengtao, Fu, Yunhe
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226486/
https://ncbi.nlm.nih.gov/pubmed/27285988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9863
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