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Development of Stem Cell-derived Antigen-specific Regulatory T Cells Against Autoimmunity

Autoimmune diseases arise due to the loss of immunological self-tolerance. Regulatory T cells (Tregs) are important mediators of immunologic self-tolerance. Tregs represent about 5 - 10% of the mature CD4(+) T cell subpopulation in mice and humans, with about 1 - 2% of those Tregs circulating in the...

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Bibliografske podrobnosti
izdano v:J Vis Exp
Main Authors: Haque, Mohammad, Fino, Kristin, Sandhu, Praneet, Song, Jianxun
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226103/
https://ncbi.nlm.nih.gov/pubmed/27911371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54720
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