Preparation of Homogeneous MALDI Samples for Quantitative Applications

This protocol demonstrates a simple sample preparation to reduce spatial heterogeneity in ion signals during matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. The heterogeneity of ion signals is a severe problem in MALDI, which results in poor data reproducibility and makes MALD...

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Vydáno v:J Vis Exp
Hlavní autoři: Ou, Yu-Meng, Tsao, Chien-Wei, Lai, Yin-Hung, Lee, Hsun, Chang, Huan-Tsung, Wang, Yi-Sheng
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2016
Témata:
Biochemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226074/
https://ncbi.nlm.nih.gov/pubmed/27842361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54409
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