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Galectin-3 Inhibition by a Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis

PURPOSE: Corneal neovascularization and scarring commonly lead to significant vision loss. This study was designed to determine whether a small-molecule inhibitor of galectin-3 can inhibit both corneal angiogenesis and fibrosis in experimental mouse models. METHODS: Animal models of silver nitrate c...

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Bibliographische Detailangaben
Veröffentlicht in:Invest Ophthalmol Vis Sci
Hauptverfasser: Chen*, Wei-Sheng, Cao, Zhiyi, Leffler, Hakon, Nilsson, Ulf J., Panjwani, Noorjahan
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225999/
https://ncbi.nlm.nih.gov/pubmed/28055102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20009
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