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Transforming growth factor beta stimulates urokinase-type plasminogen activator and DNA synthesis, but not prostaglandin E2 production, in human synovial fibroblasts.

Transforming growth factor beta (TGF-beta) is usually associated with matrix formation and tissue repair; in contrast, cellular expression of the serine proteinase, urokinase-type plasminogen activator (u-PA) is often correlated with tissue remodeling, as well as with cell migration and transformati...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Hamilton, J A, Piccoli, D S, Leizer, T, Butler, D M, Croatto, M, Royston, A K
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52257/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1908092/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.16.7180
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